Jose R Roques Selected Research

harmol

7/2021

Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies.

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Jose R Roques Research Topics

Disease

5	Neoplasms (Cancer) 07/2021 - 12/2017
1	Glioblastoma (Glioblastoma Multiforme) 07/2021
1	Brain Neoplasms (Brain Tumor) 07/2021
1	Glioma (Gliomas) 07/2021
1	Triple Negative Breast Neoplasms 01/2021
1	Diarrhea 01/2020
1	Dysbiosis 01/2020
1	Genetic Predisposition to Disease (Genetic Predisposition) 07/2012

Drug/Important Bio-Agent (IBA)

1	harmolIBA 07/2021
1	Carbolines (Beta-Carbolines)IBA 07/2021
1	Monoamine Oxidase (MAO)IBA 07/2021
1	Harmine (Telepathine)IBA 07/2021
1	Dyrk KinasesIBA 07/2021
1	ClaudinsIBA 01/2021
1	liposomal doxorubicin (Doxil)FDA Link 01/2021
1	CollagenIBA 01/2021
1	takinibIBA 05/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2020
1	EnzymesIBA 01/2020
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2020
1	Irinotecan (Camptosar)FDA LinkGeneric 01/2020
1	GlucuronidaseIBA 01/2020
1	GANT 61IBA 12/2017
1	CD40 Ligand (CD40L)IBA 07/2012
1	AutoantibodiesIBA 07/2012
1	Interleukin-6 (Interleukin 6)IBA 07/2012

Therapy/Procedure

1	Radiotherapy 01/2021